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. 2022 Jun 28;12:10891. doi: 10.1038/s41598-022-15023-x

Table 4.

Results of multiple regression analyses to estimate the association between myopia and intraocular higher order aberrations (evaluated with natural pupillary diameters, average value φ = 6.1 mm).

Axial length, mm (N = 59) Cycloplegic objective refraction, D (N = 25)
β 95% CI P β 95% CI P
Overall
Age (years) 0.183 0.086 to 0.280  < 0.001 0.314 − 0.213 to 0.842 0.26
Gender 0.178 − 0.375 to 0.731 0.53 − 0.910 − 3.03 to 1.21 0.41
SA (μm) 1.53 − 0.473 to 3.52 0.14 − 5.06 − 29.2 to 19.1 0.69
S3 (μm) − 21.8 − 40.0 to − 3.55 0.02 96.9 11.6 to 182 0.04
S4 (μm) − 9.08 − 24.2 to 6.04 0.24 58.3 − 50.7 to 167 0.31
THOA (μm) 21.2 0.634 to 41.8 0.048 − 112 − 221 to − 2.65 0.049
R2 0.365 0.285

D diopters, SA spherical aberration, S3 3rd-order aberrations, S4 4th-order aberrations, THOA sum of the 3rd- to 6th-order aberrations, 95% CI 95% confidence interval, β coefficient Two multiple regression models were used. Axial length or cycloplegic objective refraction was used as the outcome variable. P < 0.05 are highlighted. For gender, boys were numbered 1 and girls were numbered 0.