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. 2022 Jun 28;12:10891. doi: 10.1038/s41598-022-15023-x

Table 5.

Results of multiple regression analyses to estimate the association between myopia and total ocular higher order aberrations (evaluated with natural pupillary diameters, average value φ = 6.1 mm).

Axial length, mm (N = 59) Cycloplegic objective refraction, D (N = 25)
β 95% CI P β 95% CI P
Overall
Age (years) 0.171 0.070 to 0.273 0.002 0.126 − 0.413 to 0.665 0.65
Gender 0.244 − 0.350 to 0.839 0.42 − 0.875 − 3.15 to 1.40 0.46
SA (μm) − 0.123 − 3.16 to 2.91 0.94 3.03 − 6.20 to 12.3 0.53
S3 (μm) − 41.7 − 81.7 to − 1.79 0.045 106 − 89.4 to 302 0.30
S4 (μm) − 23.8 − 50.2 to 2.60 0.08 61.5 − 78.2 to 201 0.40
THOA 43.6 0.954 to 86.3 0.049 − 119 − 332 to 94.3 0.29
R2 0.278 0.155

D diopters, SA spherical aberration, S3 3rd-order aberrations, S4 4th-order aberrations, THOA sum of the 3rd- to 6th-order aberrations, 95% CI 95% confidence interval, β coefficient. Two multiple regression models were used. Axial length or cycloplegic objective refraction was used as the outcome variable. P < 0.05 are highlighted. For gender, boys were numbered 1 and girls were numbered 0.