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Loss of miR-124 is responsible for DAPK1 elevation in TBI. (A) Alterations in predicted miRNAs that target DAPK1 in the perilesional cortex of sham and TBI mice. (B) The binding sites of miR-124 with DAPK1 are conserved in mammalians. (C) The WT and Mut of DAPK1 were subcloned into the pSI-Check2 vector and transfected into HEK 293T together with miR-124 or NC mimics. The luciferase intensity was measured. n = 3 for each group; **p < 0.01; Values are presented as the mean ± SEM.
