Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 15;16:892197. doi: 10.3389/fncel.2022.892197

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Shi, Cui, Wang, Zhou, Wu, Wang, Zhang, Hu, Han, Du, Ge, Liu and Qu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Overexpression of miR-124 or knockdown DAPK1 rescued memory and motor change after TBI. (A) Experimental timeline of AAV injection, TBI induction and behavior tests. (B) The Expression level of miR-124 in the perilesional cortex at different time points and different dose after agomir delivery. (C) Fluorescence image represent expression of AAV-shDAPK1 in the cortex, and quantitative analysis of the expression level of DAPK1 after AAV-shDAPK1 or AAV-Con injection. Scale bar, 100 μm. (D) Representative open field activity tracks and statistical analysis of total distance traveled and recognition index after AAV-shDAPK1 or AAV-Con injection. (E) The representative open field activity tracks and statistical analysis of total distance traveled and recognition index after agomir or scramble injection. n = 6 for each group; **p < 0.01; Values are presented as the mean ± SEM.