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. 2022 Jun 15;10:902298. doi: 10.3389/fcell.2022.902298

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Copyright © 2022 Yang, Shan, Zhao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of the CpG signature with common clinical features. (A,B) Distribution of the risk scores in LGGs stratified by histological grade and IDH mutation status. (C,G) Distribution of the risk scores in IDH-mutant LGGs stratified by chromosome 1p/19q codeletion status and supervised DNA methylation cluster. (D–F,H) Distribution of the risk scores in IDH wild-type LGGs stratified by TERT promoter status, chromosome 7gain/10loss, EGFR amplification and supervised DNA methylation cluster.