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. 2022 Jun 15;13:892859. doi: 10.3389/fmicb.2022.892859

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Copyright © 2022 Wu, Mo, Mu, Liu, Liu and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fungal OTUs and the 16S OTUs associated with clinical metabolic parameters was determined by Mantel analysis. The co-occurrence network shows the correlations of the fungal and bacterial microbiota with the clinical metabolic parameters. The color of lines between nodes indicate significant (red line: positive correlations with P < 0.01 and green line: positive correlations with P < 0.05) or non-significant (blue line) correlations. Blue nodes: bacterial and fungal microbiota involved in GDM group; red nodes: the clinical metabolic parameters. Asterisk in square indicating relationship between the clinical metabolic parameters, **P < 0.01, *P < 0.05.