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. 2022 Jun 29;81:104132. doi: 10.1016/j.ebiom.2022.104132

Figure 7.

Figure 7

Antiviral activity of molnupiravir against 229E and OC43 in hAOs cultured at 37 °C. (A) The inhibitory effect of molnupiravir against 229E in hAOs cultured at 37 °C (n= 4–9). (B) IC50 and CC50 of molnupiravir in hAOs infected with 229E and cultured at 37 °C (n = 6–8). (C) The inhibitory effect of molnupiravir against OC43 in hAOs cultured at 37 °C (n = 4–9). (D) IC50 and CC50 of molnupiravir in hAOs infected with OC43 and cultured at 37 °C (n = 6–8). (E) and (F) The inhibitory effect of low concentration (2.5 μM) and high concentration (50 μM) of molnupiravir by immunostaining dsRNA in hAOs cultured at 37 °C. Scale bar = 25 μm. *P < 0.05; **P < 0.01; ***P < 0.001.