Figure 1.

Heterozygosity frequency and coverage of patient and healthy populations by the three SNPs

(A) Heterozygosity frequency of each of the three chosen SNPs in the healthy (left) and patient (right) populations. Heterozygosity frequency was similar among the healthy and patient populations for each of the three SNPs. rs10414837, p = 0.126, odds ratio = 0.653; rs3761005, p = 0.9615, odds ratio = 1.014; rs1683564, p = 0.9475, odds ratio = 1.019; all analyzed by chi-square. (B) Pie chart presenting the percentages of the population being heterozygous for at least one of the three chosen SNPs (gray) in the healthy (left) or patient (right) population. The healthy and patient populations are covered similarly by the three SNPs (more than 75%, p = 0.1285, odds ratio = 0.56, chi-square).