Table 2:
Disease-free survival |
Thymoma-related survival |
||||
---|---|---|---|---|---|
Univariable | Multivariable |
Univariable | Multivariable | ||
P-Value | HR (95% CI) | P-Value | P-Value | HR (95% CI) | |
Age (<56 versus ≥56) years | 0.90 | – | – | 0.98 | – |
Gender (M versus F) | 0.75 | – | – | 0.14 | – |
Charlson index (0–2 versus 3–7) | 0.35 | – | – | 0.29 | |
WHO histology (A, AB, B1 versus B2, B3) | <0.001 | 5.5 (2.0–15.0) | 0.001 | 0.16 | – |
Masaoka stage (I versus II, III) | 0.010 | – | 0.93 | 0.99 | – |
Tumour size (<63 versus ≥63) mm | 0.024 | – | 0.16 | 0.22 | – |
Extent of resection (thymomectomy versus thymectomy) | 0.12 | – | – | 0.38 | – |
Surgical approach (minimal versus open) | 0.69 | – | – | 0.69 | – |
Residual tumour (absent versus present) | <0.001 | 7.5 (2.7–21.0) | <0.001 | 0.95 | – |
Chemotherapy (none versus adjuvant) | <0.001 | 1.6 (1.0–2.6) | 0.048 | 0.93 | – |
Radiotherapy (none versus adjuvant) | 0.18 | – | – | 0.36 | – |
F: female; CI: confidence interval; HR: hazard ratio; M: male; WHO: World Health Organization.