Table 1.
Reference (quality rating) | Transmission event, setting, date | No of cases | Outcome and exposure assessment | Potential for other transmission routes | Potential for airborne transmission >2 m* | Modifying factors |
---|---|---|---|---|---|---|
Li et al,34 Lu et al,49 Zhang et al50 (medium) | Restaurant, China, January 2020 | Ten confirmed cases from three tables | No genomic sequencing. Epidemiological data, video recording, on-site visit, design of air conditioning and ventilation system, experiments to assess airflow and ventilation rates | Close contact or fomite transmission unlikely (except for cases in same household). Transmission from outside event possible for some cases | Possible airborne transmission between primary case and at least two secondary cases; up to 1.4 m (53 min) and 4.6 m (75 min) from primary case | Insufficient air replacement. Directional air flow through air circulation units |
Shen et al36 (medium) | Buses, China, January 2020 | Twenty four confirmed cases | No genomic sequencing. Questionnaires and interviews, contact tracing data, bus design, and ventilation system | Close contact, fomite transmission, or transmission from outside event possible for some cases | Possible airborne transmission >2 m from primary case (50 min) | Insufficient air replacement. Directional air flow from central heating system |
Luo et al,37 Ou et al51 (low) | Buses, China, January 2020 | Nine confirmed cases | No genomic sequencing. Epidemiological data, information on loading and unloading stops of all passengers, and seating positions, ventilation systems, tracer gas experiments | Close contact unlikely. Fomite transmission or transmission from outside event possible for some cases | Possible airborne transmission >2 m for some cases (1 hour to 2.5 hours) | Insufficient air replacement. Directional air flow due to exhaust system |
Lin et al38 (low) | Apartment block, China, January 2020 | Nine confirmed cases from three households | No whole genome sequencing (partial S gene only). Interviews with cases, CCTV of lift, tracer gas and wind speed experiments | Close contact or fomite transmission unlikely (except for cases in same household); transmission from outside event possible for some cases | Possible airborne transmission between cases in one flat to two different flats (up to 10 floors from flat of primary case) | Insufficient air replacement. Directional air flow through drainage and exhaust system |
Kwon et al35 (high) | Restaurant, South Korea, June 2020 | Three confirmed cases | Genomic sequencing. Contact tracing, interviews, credit card records, video recording, mobile phone location data, on-site visits, air flow measurement, environmental sampling | Close contact, fomite transmission, or transmission from outside event unlikely | Possible airborne transmission between cases seated 4.8 m (21 min) and 6.5 m (5 min) from the primary case | Insufficient air replacement. Directional air flow through air circulation units |
Hwang et al39 (low) | Apartment block, South Korea, August 2020 | Ten confirmed cases from seven households | No genomic sequencing. Epidemiological data, surface sampling, building assessment | Close contact or fomite transmission unlikely (except for cases in same household). Transmission from outside event possible | Possible airborne transmission through ventilation ducts across floors for some secondary cases | Directional air flow through vertical air duct or floor drain. Insufficient air replacement (unclear) |
Eichler et al32 (medium) | Quarantine hotel, New Zealand, August-September 2020 | Nine confirmed cases, with one secondary case considered for long distance transmission | Genomic sequencing. Epidemiological data, surveillance video, review of ventilation system in hotel | Close contact or fomite transmission unclear. Transmission from outside event unlikely | Possible airborne transmission from hotel room of the primary case to doorway or corridor for one secondary case | Insufficient air replacement. Directional air flow |
Han et al40 (low) | Apartment block, South Korea, January 2021 | Five secondary cases (three households) considered for long distance transmission | Genomic sequencing. Epidemiological data, interviews, mobile phone location tracking, surface sampling | Close contact or fomite transmission unlikely (except for cases in same household). Transmission from outside event unlikely | Possible airborne transmission through floor drains across three floors for two secondary cases | Insufficient air replacement. Directional air flow through vertical floor drain |
Fox-Lewis et al33(high) | Quarantine hotel, New Zealand, July 2021 | Five confirmed cases in two rooms | Genomic sequencing. Epidemiological data, surveillance video, review of ventilation system in hotel | Close contact, fomite transmission, or transmission from outside of event unlikely | Possible airborne transmission from hotel room of primary case to hotel room for at least one secondary case (2.1 m) | Insufficient air replacement. Directional air flow |
This review’s assessment of likelihood of airborne transmission of SARS-CoV-2 over distances >2 m is based on likelihood of it occurring in some, but not necessarily all, transmission events.
Exposure distance and time are stated when known; if not stated they are categorised as not clear or not specified.