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CO-RBC maintains oxygen, redox and energy homeostasis in the kidney of IR-AKI to CKD. To investigate the effect of CO-RBC on the chronic hypoxia, disruption of energy metabolism, renal disorders, and renal redox balance, kidney was collected 14 days after renal IR with or without CO-RBC treatment, then analyzed by (A, D) immunoblot (n = 5/group), (B) ATP assay (n = 5/group), and (C, E) immunostaining. Results are expressed as the mean ± S.E.M.
