Table 3.
Comparisons between ERK 1 genotypes and clinical characteristics, biochemical-hormonal parameters
| PCOS-ERK 1 | Control-ERK 1 | Pa | |||
|---|---|---|---|---|---|
| Parameters | P-GG | P-GA | C-GG | C-GA | |
| BMI | 27,3 ± 5,06b | 30,68 ± 5,72c | 26,11 ± 5,41 | 28,38 ± 8,15 | ≤ 0.001 |
| FGS | 11,08 ± 4,01b,f | 13,73 ± 6,9c | 5,48 ± 1,84 | 7,5 ± 2,16e | ≤ 0.001 |
| HOMA-IR | 2,70 ± 2,12f | 3,13 ± 1,63c,d | 1,75 ± 0,97 | 1,89 ± 0,96 | ≤ 0.001 |
| CRP | 11,38 ± 3,05f | 11,96 ± 2,38c | 6,40 ± 4,06 | 7,06 ± 2,86e | ≤ 0.001 |
| Total testesteron | 0,71 ± 0,33f | 0,77 ± 0,39c,d | 0,53 ± 0,19 | 0,4 ± 0,21e | ≤ 0.001 |
| Triglyceride | 125,54 ± 50,53f | 110,46 ± 46,54 | 93,43 ± 39,7 | 85,1 ± 30,46e | ≤ 0.001 |
| Total Cholesterol | 196,52 ± 41,65f | 188,07 ± 45,39c | 168,9 ± 26,18 | 171,7 ± 43,5 | ≤ 0.001 |
| LDL | 116,89 ± 38,3f | 117,01 ± 44,92 | 99,28 ± 21,4 | 100,4 ± 42,05 | 0.006 |
| HDL | 54,56 ± 10,77 | 48,96 ± 9,44 | 52,53 ± 12,75 | 53,6 ± 3,87 | 0.64 |
Data presented as Mean ± SD and p < 0.05 accepted as statistically significant
a Groups were compared between P-GG,P-GA,C-GG and C-GA with; one-way ANOVA test
b p < 0.05 (P-GG vs P-GA); Tamhane test
c p < 0.05 (P-GA vs C-GG); Tamhane test
d p < 0.05 (P-GA vs C-GA); Tamhane test
e p < 0.05 (P-GG vs C-GA); Tamhane test
f p < 0.05 (P-GG vs C-GG); Tamhane test
P: PCOS (Polycystic Ovary Sydrome) Group
C: Control Group