Table 2.
Basic formulations of DiR nanoliposomes
| Liposomal composition | Formulations | ||
|---|---|---|---|
|
| |||
| DiR-CL | DiR-PL | DiR-Lf | |
| DiR (mg) | 0.3 | 0.3 | 0.3 |
| HSPC (mg) | 30.0 | 30.0 | 30.0 |
| CH (mg) | 10.0 | 10.0 | 10.0 |
| mPEG2000-DSPE (mg) | – | 11.4 | 3.0 |
| DSPE-PEG2000-COOH (mg) | – | – | 6.0 |
| H2 O (mL) | 4 | 4 | 4 |
CH: Cholesterol; CL: common blank nanoliposomes; DiR: 1,1′-dioctadecyl-3,3,3′, 3′-tetramethyl-indotricarbocyanine iodide; DiR-CL: DiR common nanoliposomes; DiR-Lf: DiR PEGylated nanoliposomes with Lf modified; DiR-PL: DiR PEGylated nanoliposomes; DSPE-PEG2000-COOH: dsteeyl phosphatidylethanolamine polyethylene glycol 2000-carboxyl; HSPC: hydrogenated soybean lecithin; Lf: lactoferrin; mPEG2000-DSPE: polyethylene glycol monoethyl ether 2000-disorieyl phosphatidylethanolamine; PL: PEGylated blank nanoliposomes.