Table 3.
Particle size, PI, EE and Lf grafting ratio of BR nanoliposomes and DiR nanoliposomes
| Particle size (nm) | PI (1 h) | EE (%) | Lfgrafted (%) | |
|---|---|---|---|---|
| BR-CL | 129.5±4.6 | 0.235±0.012 | 92.1±3.0 | – |
| BR-PL | 100.4±3.2 | 0.216±0.015 | 94.7±2.4 | – |
| BR-Lf | 118.6±4.5 | 0.246±0.017 | 90.4±1.2 | 65.9±2.2 |
| DiR-CL | 128.7±3.9 | 0.207±0.014 | 95.8±4.2 | – |
| DiR-PL | 105.2±4.1 | 0.212±0.015 | 97.2±3.6 | – |
| DiR-Lf | 120.6±3.5 | 0.228±0.013 | 96.5±2.9 | 66.2±3.8 |
BR: Berberine hydrochloride; BR-CL: BR common nanoliposomes; BR-Lf: BR PEGylated nanoliposomes with Lf modified; BR-PL: BR PEGylated nanoliposomes; CL: common blank nanoliposomes; DiR: 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indotricarbocyanine iodide; DiR-CL: DiR common nanoliposomes; DiR-Lf: DiR PEGylated nanoliposomes with Lf modified; DiR-PL: DiR PEGylated nanoliposomes; EE: entrapment efficiency; Lf: lactoferrin; Lfgrafted: Lf grafting ratio; PI: performance index; PL: PEGylated blank nanoliposomes.