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. 2022 Apr 25;18(1):194–199. doi: 10.4103/1673-5374.343892

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Copyright: © Neural Regeneration Research

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NBP reverses weight loss and alleviates motor disturbance induced by rotenone.

(A) The timeline of the establishment of the rotenone-induced rat model of Parkinson’s disease, and time points of the experiments. (B) NBP inhibited rotenone-induced weight loss in rats. (C–E) Quantitative results of latency to fall in the rotarod test (C), score in the beam balance test (D), and foot fault rate in the foot fault test (E). All data are shown as the mean ± SEM (n = 15–20 rats per group). ***P < 0.001 (one-way analysis of variance followed by Tukey’s post hoc test). NBP: DL-3-n-butylphthalide.