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LTG reduced Aβ1–42 levels in the brains of APP/PS1 mice.
The concentration of Aβ1–42 in the brains was measured using an enzyme-linked immunosorbent assay. Data are expressed as means ± SD (n = 8). ###P < 0.001, vs. APP/PS1 mice (Student’s t-test). APP/PS1: Amyloid precursor protein/presenilin 1; Aβ: amyloid-β; LTG: lamotrigine; WT: wild-type.
