Table 2.
Bivariate correlation analysis between serum GDF-15 and clinical variables in IPF patients.
| Clinical variables | r | p-value |
|---|---|---|
| Population demography | ||
| Gender | -0.064 | 0.507 |
| Age (years) | -0.021 | 0.832 |
| Smoking (pack*years) | 0.046 | 0.634 |
| Inflammation and infection | ||
| WBC counts (×109) | 0.125 | 0.196 |
| ESR (mm/h) | 0.314 | 0.001 |
| CRP (mg/L) | 0.376 | <0.001 |
| LDH (U/L) | 0.272 | 0.004 |
| PCT | 0.426 | 0.01 |
| Metabolism | ||
| TG (mmol/L) | -0.201 | 0.037 |
| TC (mmol/L) | -0.229 | 0.017 |
| TCHL (mmol/L) | -0.100 | 0.302 |
| LCHL (mmol/L) | -0.255 | 0.008 |
| Apo AI (g/L) | -0.185 | 0.056 |
| Apo B (g/L) | -0.242 | 0.011 |
| ALB (g/L) | -0.318 | 0.001 |
| GLU (mmol/L) | -0.018 | 0.850 |
| Disease severity | ||
| D-dimer (mg/L) | 0.281 | 0.004 |
| PaO2/FiO2 ratio | -0.297 | 0.003 |
| HRCT score | 0.330 | 0.001 |
| PAH (mmHg) | 0.322 | 0.004 |
| FVC % pred | -0.222 | 0.033 |
| TLC % pred | -0.325 | 0.003 |
| DLCO % pred | -0.359 | 0.001 |
| GAP stage (I/II+III) | 0.305 | 0.003 |