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. 2022 Jun 15;13:891448. doi: 10.3389/fimmu.2022.891448

Table 3.

Risk factors for AE by logistic regression analysis in patients with IPF.

Clinical Variables Univariate Logistic Analysis Multivariate Logistic Analysis
HR 95.0% CI p-value HR 95.0% CI p-value
Prior corticosteroid use 3.673 1.605-8.404 0.002 5.236 0.799-34.326 0.084
PaO2/FiO2 (<300) 0.011 0.003-0.043 <0.001 0.021 0.004-0.106 <0.001
GAP stage (I/II/III) 5.227 1.771-15.422 0.003 2.435 0.798-7.542 0.117
Serum GDF-15 (>989.3 pg/ml) 0.246 0.110-0.553 0.001 0.148 0.024-0.914 0.040