TABLE 1.
Clinical and laboratory data for specimens and the T. pallidum isolatea
| Sample/isolate IDb | Collection yr | Gender | Sexual orientationc | Syphilis stage | Site of lesion | Antibody titer (assay)d | qPCR (T. pallidum gDNA in extract) (copies/μL) | RNPCT | Extraction method | Reference or source |
|---|---|---|---|---|---|---|---|---|---|---|
| CDC-SF003 | 2017 | Male | MSM | Primary | Penis | 1:4 (VDRL) | 9,680 | NA | Standard | 11 |
| EUHM-001 | 2019 | Male | MSM | Secondary | Neck | 1:128 (RPR) | <1 | 29.59 ± 0.20 | Standard | This study |
| EUHM-002 | 2019 | Male | MSM | Secondary | Perianal | 1:256 (RPR) | <1 | 28.15 ± 0.04 | Standard | This study |
| EUHM-003 | 2019 | Male | MSM | Secondary | Penis | 1:32 (RPR) | <1 | 29.35 ± 0.08 | Standard | This study |
| EUHM-004 | 2019 | Male | MSM | Primary | Penis | 1:4 (RPR) | 106.7 ± 6.5 | 25.48 ± 0.04 | Standard | This study |
| EUHM-005 | 2019 | Male | MSM | Secondary | Penis | 1:64 (RPR) | <1 | 33.34 ± 0.03 | Standard | This study |
| EUHM-006 | 2019 | Male | MSM | Primary | Penis | 1:16 (RPR) | <1 | 31.62 ± 0.03 | Standard | This study |
| EUHM-007 | 2019 | Male | MSM | Secondary | Hand | 1:64 (RPR) | <1 | 38.32 ± 0.1 | Standard | This study |
| EUHM-008 | 2019 | Male | MSM | Secondary | Scrotum | 1:64 (RPR) | 0.9 ± 0.1 | 31.00 ± 0.1 | Standard | This study |
| EUHM-009 | 2019 | Male | MSM | Secondary | Scrotum | 1:64 (RPR) | <1 | 33.24 ± 0.14 | Standard | This study |
| EUHM-010 | 2019 | Male | MSM | Secondary | Scrotum | 1:128 (RPR) | <1 | 31.27 ± 0.08 | Standard | This study |
| EUHM-011 | 2019 | Male | MSM | Primary | Penis | 1:32 (RPR) | <1 | 32.87 ± 0.21 | Standard | This study |
| EUHM-012 | 2019 | Male | MSM | Primary | Penis | 1:8 (RPR) | 31.5 ± 0.5 | 22.61 ± 0.08 | Large scale | This study |
| EUHM-013 | 2020 | Male | MSM | Secondary | Penis | 1:64 (RPR) | 122 ± 1.2 | 31.38 ± 0.21 | Large scale | This study |
| EUHM-014 | 2020 | Male | MSM | Secondary | NA | 1:16 (RPR) | 103 ± 6.7 | 24.06 ± 0.1 | Large scale | This study |
| STLC-001 | 2020 | Male | MSW | Primary | Penis | NR (RPR) | 28.8 ± 3.1 | 25.57 ± 0.07 | Standard | This study |
a
NA, not available; NR, nonreactive.
b
EUHM, Emory University Hospital, Atlanta, GA; STLC, St. Louis County STD Clinic, St. Louis. MO.
c
MSM, men who have sex with men; MSW, men who have sex with women.
d
VDRL, Venereal Disease Research Laboratory test; RPR, rapid plasma reagin test.