TABLE 2.
RT-PCR-identified diagnostic sensitivity and specificity of the multiplex bead assay kit by overall call and individual antigen targetsa
| Target | Sensitivity (%) |
Specificity (%) |
||||
|---|---|---|---|---|---|---|
| Valueb | LL | UL | Valueb | LL | UL | |
| Overall | 89.80 | 84.68 | 93.65 | 100.00 | 96.87 | 100.00 |
| RBD | 91.84 | 87.08 | 95.26 | 95.69 | 90.23 | 98.59 |
| NP | 92.86 | 88.31 | 96.04 | 94.83 | 89.08 | 98.08 |
| RBD/NP fusion | 90.82 | 85.87 | 94.47 | 100.00 | 96.87 | 100.00 |
a
RT-PCR, reverse transcriptase PCR; n = 312 specimens with full data available for analysis.
b
Values with 95% confidence intervals (LL, lower limit; UL, upper limit) were calculated for the assays’ overall call and for each individual antigen (RBD, receptor binding domain of spike protein; NP, nucleocapsid protein).