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. 2022 Apr 25;10(3):e00177-22. doi: 10.1128/spectrum.00177-22

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Copyright © 2022 Jing et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 7 — Differential amounts of metabolites among the sham, SCI and SCI+FMT groups. (A) PLS-DA score plot based on metabolic profiles in fecal samples from the sham, SCI and SCI+FMT groups. (B) Score scatterplot of OPLS-DA revealing the separation among groups according to metabolic differences. (C) Metabolites significantly altered in sham animals versus SCI group and SCI group versus SCI+FMT group. Those with VIP >1.0 and P < 0.05 (t test) were identified. Venn diagrams demonstrating the amounts of altered metabolites shared among the three groups by the overlap (n = 8). (D) Relative amounts of 22 differentially produced metabolites in the three groups, presented as a heat map.