Figure 2.
Disease associations of class sums and total FA sums. Hazard ratios from models adjusted for age (as underlying time variable), sex, waist circumference, height, leisure time physical activity, smoking status, alcohol intake, highest achieved education level, fasting status at blood draw, total energy intake, blood pressure (systolic and diastolic), blood lipids (total cholesterol, high-density lipoprotein cholesterol, and standard clinical triacylglycerol), antihypertensive medication, lipid-lowering medication, and acetylsalicylic acid medication. Models for cardiovascular disease further adjusted for antidiabetic medication and proportion glycohemoglobin. A, Class sums; B, total FA sums, additionally adjusted for all class sums. CE indicates cholesteryl esters; Cer, ceramides; CVD, cardiovascular disease; DG, diacylglycerols; dhCer, dihydroceramides; FA, fatty acids; FFA, free fatty acids; HexCer, hexosylceramides; LacCer, lactosylceramides; LPC, lysophosphatidylcholines; LPE, lysophosphatidylethanolamines; MG, monoacylglycerols; PC, phosphatidylcholines; PE, phosphatidylethanolamines; PEO, phosphatidylethanolamine ether; PEP, phosphatidylethanolamine plasmalogen; PI, phosphatidylinositol; SM, sphingomyelins; and TG, triacylglycerols.