TABLE 2.

MICs and susceptibility interpretation of omadacycline and comparator agents against 10 carbapenem-nonsusceptible clinical A. baumannii isolates included in time-kill experiments^a

Isolate	Amikacin		Meropenem		Minocycline		Omadacycline		Polymyxin B		Rifampin		Sulbactam		Tigecycline
AB1	32	I	16	R	0.25	S	4	NC	0.5	I	4	NC	128	R	8	NC
AB2	32	I	≥256	R	2	S	16	NC	0.25	I	16	NC	32	R	8	NC
AB3	8	S	4	I	16	R	8	NC	0.5	I	16	NC	32	R	4	NC
AB4	>256	R	128	R	16	R	16	NC	>64	R	>256	NC	16	R	16	NC
AB5	32	I	≥256	R	16	R	1	NC	0.25	I	16	NC	64	R	2	NC
AB6	>256	R	≥256	R	8	I	4	NC	>64	R	16	NC	16	R	4	NC
AB7	32	I	≥256	R	1	S	2	NC	0.25	I	8	NC	16	R	2	NC
AB8	>256	R	≥256	R	4	S	4	NC	0.25	I	4	NC	32	R	2	NC
AB9	2	S	16	R	8	I	1	NC	0.25	I	8	NC	16	R	1	NC
AB10	4	S	64	R	2	S	8	NC	0.5	I	8	NC	64	R	4	NC

^aGray shaded cells represents isolates for which the respective drug’s free maximum concentration of drug in serum (fC_max) was ≥MIC. NC, no applicable interpretive criteria.