TABLE 1.
Profile | K. pneumoniae colonyb | Phage lytic activityc |
|||||
---|---|---|---|---|---|---|---|
Profile | JIPh_ Kp192 | JIPh_Kp193 | JIPh_ Kp202 | JIPh_Kp195 | JIPh_Kp194, 196, 197, 198, 199 | ||
JN-1 | a (ST307), c (ST307) | A | Good | Poor | None | None | None (a, c) |
JN-1 | b (ST628), 1, 2, 4, 5, 6, 9, 13, 21-23, 25, 33, 35-39, 49, 53-55 | B | None | Good | None | Good | Good (b) |
JN-1 | d, 3, 7, 11, 12, 14-18, 24, 26, 29, 31, 32, 34, 40, 42 (ST307), 44, 46-48, 50, 52, 56-61 | C | Good | None | None | None | Nt |
JN-1 | 8, 10, 19, 20, 27, 30, 41, 45, 51 | D | None | None | None | None | Nt |
JN-1 | 28 | E | None | Poor | None | Poor | Nt |
JN-1 | 43 | F | Poor | None | None | None | Nt |
JN-2 | a (ST628), c (ST628), 1, 3-5, 7, 9, 14, 18, 19, 22-24, 27-29, 31, 33-41, 44, 45, 49-51, 53, 54, 58, 59 | B | None | Good | None | Good | Good (a, c) |
JN-2 | 11, 12 | C | Good | None | None | None | Nt |
JN-2 | 8, 15 (ST392), 21, 26 (ST4656), 42, 52, 60 | D | None | None | None | None | Nt |
JN-2 | b (ST893), d (ST893), 6, 10, 13, 16, 17, 20, 25, 30, 32, 43, 46-48, 55-57, 61 | G | None | None | Good | None | None (b, d) |
JN-2 | 2 | H | None | None | Poor | None | Nt |
JIPh phages against K. pneumoniae were isolated de novo from sewage, human and animal feces, river water, and horse tracheal aspirates (TA).bIn bold colonies with unique phage susceptibility profiles selected for further characterization including JN1 a, b, c and JN2 a, b, c, d (the seven strains initially used as targets for de novo bacteriophage isolation).cGood, complete lysis (clear spots); Poor, partial lysis (turbid spots); None, no lysis; Nt, not tested.