TABLE 1.

Summary of phenotypic susceptibility tests and genotypic predictions for 494 isolates

Category/drug	True positivea	True negativeb	False positivec	False negatived	Sensitivity (%)	Specificity (%)
First-line
Isoniazid	409	44	5	36	91.9	89.8
Rifampicin	367	57	62	8	97.9	47.9
Ethambutol	126	236	126	6	95.5	65.2
Pyrazinamide	119	292	21	62	65.8	93.3
Second-line
Streptomycin	148	258	10	78	65.5	96.3
Kanamycin	19	453	9	13	59.4	98.1
Amikacin	15	466	2	11	57.7	99.6
Capreomycin	16	465	5	8	66.7	98.9
Ofloxacin	102	365	18	9	91.9	95.3
Levofloxacin	83	368	37	6	93.3	90.9
Moxifloxacin	71	369	49	5	93.4	88.3
Ethionamide	70	338	32	54	56.5	91.4

^aTrue positive, phenotypically resistant, and contained known resistance-conferring mutations.

^bTrue negative, phenotypically susceptible, and no known resistance-conferring mutations.

^cFalse positive, phenotypically susceptible but known resistance-conferring mutations.

^dFalse negative, phenotypically resistant but no known resistance-conferring mutations.