TABLE 1.

Antifungal susceptibility changes associated with GCN5 deletion

Antifungal agent	Time of readout (h)	MIC (μg/mL)
		WT	gcn5Δ	gcn5Δ::GCN5
Itraconazole	24	0.25	0.125	0.25
	48	1	0.25	1
Posaconazole	24	0.5	0.125	0.5
	48	1	0.5	1
Voriconazole	24	0.5	0.25	0.5
	48	1	0.5	1
Fluconazole	24	16	8	16
	48	32	16	32
Anidulafungin	24	0.03	0.015	0.03
Caspofungin	24	0.06	0.06	0.06
Micafungin	24	0.03	0.008	0.015
Manogepix	24	0.064	≤0.008	0.03
Ibrexafungerp	24	0.5	0.25	0.5