TABLE 2.

Deletion of GCN5 increases echinocandin susceptibility and reverses Fks1-mediated echinocandin resistance by FK506

Strain	24-h MIC (μg/mL)
	Micafungin	FK506	Micafungin + FK506 (4 μg/mL)
WT	0.03	32	0.015
gcn5Δ	0.008	8	≤0.001
S629P	0.5	32	0.25
S629P_gcn5Δ	0.125	16	≤0.03
F625del	0.5	32	0.125
F625del_gcn5Δ	0.125	8	≤0.03
S663P	4	32	1
S663P_gcn5Δ	2	16	0.5
F659del	2	16	0.25
F659del_gcn5Δ	0.5	≤0.125	≤0.03