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. 2022 Jun 6;10(3):e00125-22. doi: 10.1128/spectrum.00125-22

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Copyright © 2022 Fang et al.

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FIG 3 — Antibiotic administration negates the protective effect of IPA supplementation. (A) The schematic diagram showed experimental design and procedures for antibiotic (Abx) administration. (B) Gut microbiota alpha diversity was assessed by the Shannon and Ace indices in antibiotic-treated and normal mice. (C) Gut microbiota alpha diversity was assessed by the Shannon and Ace indices in the IPA-treated and saline-treated mice after antibiotic administration. (D) Scatterplots of PCoA showed gut microbiota beta diversity between the IPA-treated and saline-treated mice after antibiotic administration. (E) Survival rate. The serum levels of IL-1β (F) and TNF-α (G) were measured using ELISA. n = 6 to 10. #, P > 0.05.