TABLE 2.

Selected microRNAs identified by microarray for RT-qPCR verification^a

miRNA	miRNA expression levels for TB cases vs LTBI controls
	Agilent microarray results (case group, n = 20; control group, n = 20)			RT-qPCR results (case group, n = 73; control group, n = 77)
	Fold-change	P b	Regulation	Fold-change	P b	Regulation
hsa-miR-16-5p	0.27	<0.001	Down	0.45	<0.001	Down
hsa-miR-197-5p	2.59	<0.001	Up	0.99	0.482	NA
hsa-miR-451a	0.42	0.009	Down	0.22	<0.001	Down
hsa-miR-671-5p	2.81	<0.001	Up	0.63	0.005	Down
hsa-miR-6760-3p	2.77	<0.001	Up	2.08	0.043	Up

^aRT-qPCR, real-time quantitative PCR; LTBI, latent tuberculosis infection; miRNA, microRNA; TB, tuberculosis; NA, not applicable.

^bFor Wilcoxon rank-sum test, P < 0.01 was considered statistically significant.