TABLE 2.

Performance of deletion assays in saliva^a

Assay	Screening assay result	Whole genome sequencing result		Assay clinical analysis
		Reference	Deletion	% Accuracy	% Clinical sensitivity	% Clinical specificity	% PPV	% NPV
SΔ69-70	Reference	179	0	93.60 [90.57, 96.63]	100.0 [100.0]	98.35 [96.48, 100.0]	94.83 [89.13, 100.0]	100.0 [100.0]
	Deletion	3	55
	Inconclusive	11	2
ORF1aΔ3675-3677	Reference	104	0	68.00 [62.22, 73.78]	100.0 [100.0]	97.20 [94.03, 100.0]	95.65 [90.84, 100.0]	100.0 [100.0]
	Deletion	3	66
	Inconclusive	14	63

^aUpper-bound values cannot exceed 100.0%. This applies to all measurements. 95% confidence interval is represented in brackets.