TABLE 6.
Univariate and multivariate analysis of factors associated with 30-day case fatality rate
| Characteristicsa | Dead n = 53 (%) | Alive n = 98 (%) | P value | Adjusted OR (95% CI)a | P valueb |
|---|---|---|---|---|---|
| Female gender | 19 (40.4) | 28 (59.6) | 0.96 | 0.97 (0.38–2.45) | 0.958 |
| Age (yrs) (median, IQR) | 53 (18–90) | 54.5 (18–79) | 0.79 | 0.98 (0.95–1.00) | 0.133 |
| Pneumonia | 20 (58.8) | 14 (41.2) | 0.014 | 5.45 (1.84–16.13) | 0.002 |
| Therapy with ceftolozane-tazobactam | 10 (22.7) | 34 (77.3) | 0.004 | 0.19 (0.07–0.55) | 0.002 |
| Persistent bloodstream infection | 14 (63.6) | 8 (36.4) | 0.009 | 5.44 (1.61–18.31) | 0.006 |
| Infection due to XDR PA | 23 (52.3) | 21 (47.7) | 0.045 | 1.76 (0.68–4.54) | 0.240 |
| Profound neutropenia (<100 cells/mm3) | 41 (48.8) | 43 (51.2) | 0.009 | 5.49 (1.96–0.15.36) | 0.001 |
a
XDR PA, extensively drug-resistant Pseudomonas aeruginosa; OR, odds ratio; 95% CI, 95% confidence interval.
b
Bold formatting indicates statistical significance.