Figure 3.

Optoception was induced by optogenetic stimulation only. A, The number of sessions needed to reach the learning criteria. Mice were trained in optogenetic-cue sipper alternation tasks, as shown in Figure 1B, but with the laser only as a cue). Each dot represents an individual subject. B, Percent of correct cue trials. Note the drop in task performance during the “fake laser” session, demonstrating that mice used the interoceptive (or any sensory-motor) effects induced by the optogenetic stimulation only as a conditioned cue. Error bars indicate SEM.