TABLE 2.
Intraoperative results, early and long term outcomes.
| All, n = 66 | Septal thickness < 18 mm (n = 29) | Septal thickness ≥ 18 mm (n = 37) | P-value | |
| Aortic cross-clamp (min) | 41.4 ± 10.6 (20–80) | 41.9 ± 10.9 (20–65) | 41.1 ± 10.6 (24–80) | 0.7 |
| Cardiopulmonary bypass (min) | 56.5 ± 12.7 (25–105) | 56.8 ± 13.7 (25–88) | 56.2 ± 12.1 (38–105) | 0.8 |
| Resected cords (n) | 3.5 ± 1.6 (0–8) | 3.5 ± 1.6 (0–8) | 3.5 ± 1.6 (0–7) | 0.9 |
| Procedures on papillary muscles (n) | 1.3 ± 0.8 (0–3) | 1.4 ± 0.9 (0–3) | 1.2 ± 0.8 (0–2) | 0.4 |
| Mitral valve replacement | 2 (3) | 0 | 2 (3) | 0.4 |
| Intraoperative mitral valve replacement for MR | 1 (1) | 0 | 1 (1) | 0.4 |
| Posterior mitral leaflet shortening | 4 (6) | 4 (6) | 0 (0) | 0.033 |
| Other procedures | 6 (9) | 4 (6) | 2 (3) | 0.3 |
| Blood transfusion | 37 (56) | 17 (25) | 20 (30) | 0.8 |
| Re-exploration | 1 (1) | 1 (1) | 0 (0) | 0.4 |
| Low cardiac output syndrome | 2 (3) | 1 (1) | 1 (1) | 1 |
| Sepsis | 3 (4) | 1 (1) | 2 (3) | 1 |
| Post-operative atrial fibrillation | 33 (50) | 11 (16) | 22 (34) | 0.1 |
| Post-operative PM implantation | 3 (4) | 2 (3) | 1 (1) | 0.5 |
| Post-operative Complete AV block | 0 | |||
| Iatrogenic ventricular septal defect | 0 | |||
| Length of stay (days) | 10.6 ± 8.3 (5–62) | 10.1 ± 6 (5–33) | 10.9 ± 9.8 (5–62) | 1 |
| Pre-discharge SAM | 2 (3) | 1 (1) | 1 (1) | 1 |
| Pre-discharge | ||||
| LVOT gradient* (mmHg) | 15.4 ± 8.5 (0–33) | 14.7 ± 8 (0–30) | 16 ± 8.8 (0–33) | 0.5 |
| Septal thickness (mm) | 14 ± 2.6 (7–16) | 12.7 ± 1.4 (10–16) | 15 ± 2.9 (7–16) | 0.0001 |
| NYHA functional class | 1.3 ± 0.5 (1–3) | 0.7 | ||
| I–II | 63 (95) | 27 (41) | 36 (55) | 0.7 |
| III | 3 (5) | 2 (3) | 1 (1) | |
| MR grade | 1.2 ± 0.6 (0–3) | 0.2 | ||
| ≤ 1 + /4 + | 50 (75) | 25 (37.5) | 25 (37.5) | |
| 2 + /4 + | 15 (22) | 4 (6) | 11 (16) | |
| 3 + /4 + | 1 (3) | 0 | 1 (3) | |
| Hospital mortality | 0 | |||
| Follow-up | ||||
| SAM | 7 (11) | 2 (3) | 5 (8) | 0.5 |
| LVOT gradient* (mmHg) | 16.3 ± 8.8 (6–40) | 18.2 ± 9.2 (6–40) | 14.8 ± 8.2 (8–39) | 0.1 |
| Septal thickness (mm) | 13.9 ± 2.7 (9–16) | 12.9 ± 1.9 (10–18) | 14.8 ± 3 (9–16) | 0.0068 |
| NYHA functional class | 1.6 ± 0.6 (1–3) | 0.9 | ||
| I | 27 (43) | 11 (17) | 16 (25) | |
| II | 35 (54) | 16 (25) | 19 (29) | |
| III | 2 (3) | 1 (1) | 1 (1) | |
| MR grade | 1.2 ± 0.5 (0–4) | 0.6 | ||
| ≤ 2 + /4 + | 62 (98) | 28 (44) | 34 (54) | |
| 4 + /4 + | 1 (2) | 0 | 1 (1) | |
| Reoperation at follow-up for MR | 0 | |||
| Exitus at follow-up | 2 (3) | 1 (1.5) | 1 (1.5) | 1 |
MR, mitral regurgitation; PM, pacemaker; AV, atrio-ventricular; SAM, systolic anterior motion. LVOT, left ventricle outflow tract; NYHA, New York Heart Association.
*Peak gradient at rest.
Continuous variables were expressed as mean, standard deviation and range.
Categorical variables were expressed as absolute value and percentage.
Bold values are referred to the significative p value.