Table 1.
Baseline characteristics stratified by age-groups
| <65 years (n = 339) | ≥65 years (n = 342) | P-value | |
|---|---|---|---|
| Platelet-to-lymphocyte ratio (IQR) | 118.2 (91.7–154.7) | 150.2 (107.3–209.3) | <0.001 |
| Platelet count (IQR) | 247 (210–292) | 219 (178–266) | <0.001 |
| Lymphocyte count (IQR) | 2.1 (1.6–2.7) | 1.4 (1.1–2.0) | <0.001 |
| Clinical presentation | |||
| Age, years (IQR) | 45 (41–56) | 84 (73–87) | <0.001 |
| Gender (male), n (%) | 186 (54.9) | 143 (41.8) | 0.001 |
| Body mass index, kg/m2 (IQR) | 27.4 (24.7–31.1) | 25.2 (23.4–27.8) | <0.001 |
| STEMI, n (%) | 180 (53.3) | 275 (80.4) | <0.001 |
| Coronary angiography, n (%) | 293 (86.4) | 229 (67.6) | <0.001 |
| Stenting, n (%) | 276 (81.4) | 193 (56.4) | <0.001 |
| 1 vessel, n (%) | 233 (68.7) | 148 (43.3) | |
| 2 vessels, n (%) | 37 (10.9) | 33 (9.6) | |
| ≥3 vessels, n (%) | 6 (1.8) | 12 (3.5) | |
| Fibrinolysis, n (%) | 54 (16.0) | 18 (5.3) | <0.001 |
| Cardiogenic shock, n (%) | 35 (10.4) | 18 (5.3) | 0.014 |
| LVEF ≤40%, n (%) | 61 (18.0) | 110 (32.2) | <0.001 |
| Comorbidities | |||
| Hypertension, n (%) | 216 (64.1) | 269 (78.7) | <0.001 |
| Diabetes mellitus, n (%) | 53 (15.7) | 90 (26.3) | 0.001 |
| Hypercholesterolaemia, n (%) | 237 (70.3) | 218 (63.7) | 0.068 |
| Renal function failure, n (%) | 8 (2.4) | 44 (13.3) | <0.001 |
| Heart failure, n (%) | 8 (2.4) | 24 (7.3) | 0.002 |
| Current smoker, n (%) | 262 (78.4) | 98 (28.7) | <0.001 |
| Family history of CVD, n (%) | 146 (43.8) | 114 (33.3) | 0.005 |
| Laboratory analysis | |||
| Total leucocytes, G/L (IQR) | 10.3 (8.1–13.3) | 9.2 (7.0–11.5) | <0.001 |
| C-reactive protein, mg/dL (IQR) | 0.61 (0.32–1.24) | 0.82 (0.40–2.51) | 0.001 |
| Troponin T (max), µg/L (IQR) | 2.09 (0.78–4.95) | 2.18 (0.75–4.54) | 0.868 |
| Creatine kinase (max), U/L (IQR) | 910 (336–1942) | 581 (226–1352) | <0.001 |
| LDH (max), U/L (IQR) | 430 (282–698) | 419 (285–622) | 0.345 |
| Gamma-GT µkat/L (IQR) | 32 (20–52) | 28 (18–46) | 0.088 |
| Butyrylcholinesterase, U/L (IQR) | 7.4 (5.9–9.0) | 6.3 (5.5–7.6) | <0.001 |
| Total bilirubin, µmol/L (IQR) | 0.48 (0.35–0.69) | 0.64 (0.45–0.91) | <0.001 |
| Creatinine, mg/dL (IQR) | 0.98 (0.82–1.09) | 1.10 (0.93–1.36) | <0.001 |
| NT-proBNP, pg/mL (IQR) | 582 (213–1427) | 3172 (1163–7411) | <0.001 |
| Cardiovascular mortality | 34 (10.0) | 166 (48.5) | <0.001 |
Categorical data are presented as counts and percentages and analysed using χ2 test. Continuous data are presented as median and the respective interquartile range and analysed using Mann–Whitney U test.
CVD, coronary vessel disease; LDH, lactate dehydrogenase; LVEF, left ventricular ejection fraction; STEMI, ST-elevation myocardial infarction.
Significance of bold values is indicated by a p-value of <0.05.