Table 3.

Comparisons of prognostic models for predicting a composite of all-cause death and heart failure readmission

	NRI	95% CI	P-value
Baseline model (Model 1)		Reference
Baseline model + SPPB score (Model 2)
- vs. Model 1	0.139	0.008–0.270	0.036
Baseline model + 6MWD (Model 3)
- vs. Model 1	0.350	0.220–0.480	<0.001
- vs. Model 2	0.300	0.171–0.433	<0.001
Baseline model + 6MWD + SPPB score (Model 4)
- vs. Model 1	0.338	0.209–0.468	<0.001
- vs. Model 2	0.358	0.228–0.488	<0.001
- vs. Model 3	0.048	−0.083 to 0.180	0.475

6MWD, 6-minute walking distance; CI, confidence interval; NRI, net reclassification improvement; SPPB, Short Physical Performance Battery.

Takeshi Kitai, MD, PhD, has a staff physician in the department of Cardiovascular Medicine, at the National Cerebral and Cardiovascular Center in Japan. He received medical degree from Osaka City University in 2004 and PhD from Kyoto University Graduate School of Medicine in 2013. He completed his post-doc clinical research fellowship at the Cleveland Clinic in 2017. As a clinician-scientist and practicing heart failure/transplant cardiologist, Dr Kitai's research focuses on understanding pathophysiological mechanisms that contribute to disease progression in heart failure and other organ dysfunctions.