Table 2. Multivariate analysis of prognostic factors associated with hospital mortality in patients with HFNC failure.

	OR	95% CI	p
Disease status
Diagnosis	1		0.00075
Refractory or relapse	3.73	[1.08–12.86]
Remission (complete or partial)	0.2	[0.04–0.98]
Number of pulmonary quadrants on chest X-ray	1.93	[1.14–3.26]	0.01
Duration of HFNC before intubation
Day 1	1		0.017
≤ 24 hours (Day 0)	1.7	[0.3–9.75]
Day 2 and 3	0.65	[0.17–2.42]
> Day 3	7.78	[1.44–41.96]
SAPS II at ICU admission	1.06	[1–1.12]	0.019

CI: confidence interval, HFNC: high flow nasal cannula, ICU: intensive care unit, OR: odds ratio, SAPS II: Simplified Acute Physiology Score II.