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. Author manuscript; available in PMC: 2022 Jun 29.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Mar 11;1867(6):166121. doi: 10.1016/j.bbadis.2021.166121

Figure 4. Control of fatty acid synthesis and VLDL secretion by LXR.

Figure 4.

LXR directly regulates the expression of genes encoding enzymes required for fatty acid synthesis as well the gene encoding SREBP1c, a second lipogenic transcription factor. Regulation of phospholipid composition indirectly influences the lipidation and secretion of VLDL and the activity of SREBP1c. See the text for details.