Fig. 1.
Volcano plots of differential gene expression analyses in placentas from SARS-CoV-2 IgG positive (n = 15) versus IgG negative (n = 29) participants. A. Linear models adjusted for infant sex, birthweight, gestational age at birth, maternal age and pre-pregnancy BMI. B. Linear models adjusted for covariates and cell-type gene expression proxies. The x-axis is the log2 fold change (FC) and y-axis is the –log10 P-value, the highlighted in blue are genes with p < 0.05. The horizontal dashed line corresponds to p = 0.05.