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. 2021 Dec 18;414(18):5357–5371. doi: 10.1007/s00216-021-03819-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Neuroprotective effect of pre-incubation of D. salina (DS) extract against the neurotoxic agents (a) Aβ_1-42 (30 µM) and (b) l-glutamate (23 mM) in differentiated SH-SY5Y cells. Non Aβ_1-42-treated cells were used as control, together with only DS extract-treated cells at 20 μg/mL. The results are mean (n = 3) ± SD. * denotes statistical differences between control and DS extract when neurotoxic agent is added (*p < 0.05)