Table 2.
Polydisperse GAG polysaccharide samples used in this study.
| GAG sample | Mean Mw (kDa)a | PDIa (Mw/Mn) | Animal source | GAG providerb (catalogue number, or reference) |
|---|---|---|---|---|
| pHA-b | 357 | Microbial fermentation | Lifecore Biomedical (HA500K)54 | |
| pHS-b | 12 | 1.6 | Porcine intestinal mucosa | Celsus Laboratories55 |
| pCS-b | Not provided | Shark cartilage | Sigma-Aldrich (C4384) | |
| pCS-A-b | 16 | Sturgeon notochord | Seikagaku (400658) | |
| pDS-b | 30 | Porcine intestinal mucosa | Sigma-Aldrich (C3788) | |
| pCS-C-b | 60 | Shark cartilage | Amsbio (400675) | |
| pCS-D-b | 30 | Shark cartilage | Amsbio (400676) | |
| pCS-E-b | 62.5 | Squid cartilage | Seikagaku (400678) |
aMean Mw and PDI as per manufacturer’s specifications or reference provided, where available.
bAll samples were purchased without biotin tag, and biotinylated at the reducing end by oxime ligation (see Supplementary Methods for details).