Table 3.
The apparent permeability coefficient (Papp) and the efflux ratio (ER) of rhodamine-123 (2.5 μg/mL) in the absence or presence of Triphala extract.
| Compounds |
Papp (x10−5) (cm/s) |
Efflux ratio (ER) | |
|---|---|---|---|
| Apical to Basolateral | Basolateral to Apical | ||
| Rhodamine 123 (control) | 6.4 ± 1.0 | 19.0 ± 0.3 | 3.2 ± 0.5 |
| Rhodamine 123 + verapamil (5 μg/mL) | 11.0 ± 0.8∗ | 16.8 ± 0.8 | 1.6 ± 0.1∗ |
| Rhodamine 123 + Triphala extract (125 μg/mL) | 6.9 ± 0.9 | 14.8 ± 0.3 | 2.3 ± 0.5 |
Data are presented as mean ± SEM (n = 3). ∗ represents p < 0.05 as compared with control group.