TABLE 3.
Basic characteristics of patients in the training and validation cohorts.
| Characteristics | Training cohort N (%) | Validation cohort N (%) | P |
| Total | 138,391 (100) | 59,308 (100) | |
|
| |||
| Age | 0.217 | ||
| <65 | 68,952 (49.8) | 29,730 (40.1) | |
| ≥65 | 69,439 (50.2) | 29,578 (49.9) | |
| Sex | 0.442 | ||
| Female | 66,443 (48.0) | 28,587 (48.2) | |
| Male | 71,948 (52.0) | 30,721 (51.8) | |
| Race | 0.488 | ||
| Black | 16,569 (12.0) | 6,988 (11.8) | |
| White | 109,146 (78.9) | 46,869 (79.0) | |
| Other | 12,676 (9.2) | 5,451 (9.2) | |
| Year of diagnosis | 0.499 | ||
| 2007–2010 | 62,374 (45.1) | 26,632 (44.9) | |
| 2011–2015 | 76,017 (54.9) | 32,676 (55.1) | |
| Marital status | 0.305 | ||
| Married | 78,031 (56.4) | 33,179 (55.9) | |
| Unmarried | 60,360 (43.6) | 26,129 (44.1) | |
| Insurance | 0.962 | ||
| Any Medicaid | 17,421 (12.6) | 7,471 (12.6) | |
| Insured | 116,171 (83.9) | 49,766 (83.9) | |
| Uninsured | 4,799 (3.5) | 2,071 (3.5) | |
| Tumor site | 0.248 | ||
| Left | 70,638 (51.0) | 30,506 (51.4) | |
| Right | 65,713 (47.5) | 27,919 (47.1) | |
| NOS | 2,040 (1.5) | 883 (1.5) | |
| Tumor size | 0.761 | ||
| ≤5 cm | 78,372 (56.6) | 33,693 (56.8) | |
| 5–10 cm | 36,503 (26.4) | 15,575 (26.3) | |
| >10 cm | 23,516 (17.0) | 10,040 (16.9) | |
| Grade | 0.238 | ||
| Grade I | 15,014 (10.8) | 6,447 (10.9) | |
| Grade II | 96,153 (69.5) | 41,348 (69.7) | |
| Grade III | 23,354 (16.9) | 9,946 (16.8) | |
| Grade IV | 3,870 (2.8) | 1,567 (2.6) | |
| SEER stage | 0.204 | ||
| Localized | 54,182 (39.2) | 23,473 (39.6) | |
| Regional | 57,291 (41.4) | 24,371 (41.1) | |
| Distant | 26,918 (19.5) | 11,464 (19.3) | |
| Surgery | 0.711 | ||
| No | 13,042 (9.4) | 5,557 (9.4) | |
| Yes | 125,349 (90.6) | 53,751 (90.6) | |
| Radiotherapy | 0.273 | ||
| No | 118,354 (85.5) | 50,608 (85.3) | |
| Yes | 20,037 (14.5) | 8,700 (14.7) | |
| Chemotherapy | 0.434 | ||
| No | 80,949 (58.5) | 34,804 (58.7) | |
| Yes | 57,442 (41.5) | 24,504 (41.3) | |
| Death causes | 0.267 | ||
| Alive | 82,788 (59.8) | 35,456 (59.8) | |
| Death form CRC | 39,417 (28.5) | 16,768 (28.3) | |
| Death form CVD | 6,712 (4.9) | 2,990 (5.0) | |
| Death from non-CVD | 9,474 (6.8) | 4,094 (6.9) | |
Other, American Indian/Alaska Native/Asian/Pacific Islander; NOS, not otherwise specified; SEER, Surveillance, Epidemiology, and End Results; CRC, colorectal cancer; CVD, cardiovascular death.