TABLE 1.
Accuracy, precision, matrix effect and recovery of QC samples of relugolix from plasma in rats (n = 6).
| Concentration (ng/mL) | RSD (%) |
RE (%) |
Matrix Effect (%) | Recovery (%) | ||
|---|---|---|---|---|---|---|
| Intra-day | Inter-day | Intra-day | Inter-day | |||
| 0.7 | 8.4 | 11.7 | −4.3 | 8.7 | — | — |
| 1.4 | 7.1 | 8.9 | 0.0 | 10.0 | 112.6 ± 10.2 | 80.5 ± 8.5 |
| 80 | 5.0 | 6.6 | 6.1 | 12.1 | 110.7 ± 8.3 | 86.2 ± 6.0 |
| 800 | 3.0 | 4.0 | −0.3 | 2.9 | 108.8 ± 12.8 | 88.3 ± 3.5 |
RSD, relative standard deviation; RE, relative error.