Table 2.
Baseline Characteristics by Indication for PPI (After Full Review).
| On PPI, no indication (N = 47) |
On PPI, indication (N = 22) |
No PPI (N = 103) |
P-value | |
|---|---|---|---|---|
| Age—years (mean, SD) | 66 (16) | 69 (11) | 66 (14) | .65 |
| Sex (F/M) | 22/25 | 10/12 | 30/73 | .07 |
| Dialysis vintage (median, IQR) | 762 (322-1623) | 788 (579-1320) | 949 (516-2006) | .31 |
| Diabetes mellitus (N, %) | 27 (57) | 16 (73) | 51 (50) | .13 |
| Hypertension (N, %) | 34 (72) | 19 (86) | 87 (84) | .17 |
| Dyslipidemia (N, %) | 32 (68) | 21 (95) | 63 (61) | .008 |
| Coronary artery disease (N, %) | 11 (23) | 16 (72) | 31 (30) | .0001 |
| PVD (N, %) | 3 (6) | 6 (27) | 16 (16) | .07 |
| Aspirin (N, %) | 19 (40) | 18 (82) | 37 (36) | .0004 |
| NSAID (N, %) | 1 (2) | 1 (5) | 0 (0) | .09 |
| Antiplatelet (N, %) | 3 (6) | 10 (45) | 6 (6) | <.0001 |
| Anticoagulant (N, %) | 7 (15) | 1 (5) | 1 (1) | .002 |
| Prednisone | 7 (15) | 4 (18) | 5 (5) | .03 |
Note. PPI = proton pump inhibitor; N = number; F = female; M = male; IQR = interquartile range; PVD = peripheral vascular disease; NSAID = non-steroidal anti-inflammatory.