TABLE 3.

Diffusional features of motile endosomes.

		%Confined	%Diffusive	% Directed	Avg. Distance μm	DC μm2/s
Controls	UT	69.0 ± 1.7	10.60.6	19.8 ± 1.8	0.26 ± 0.01	0.0060 ± 0.0010
	CoA	69.1 ± 1.5	11.40.7	18.5 ± 1.5	0.21 ± 0.01	0.0063 ± 0.0009
	4-PBA	66.4 ± 2.3	12.21.6	21.8 ± 2.7	0.23 ± 0.2	0.0051 ± 0.0014
PKAN[Tyr190*]	UT	67.0 ± 1.3	8.90.6	24.3 ± 1.2	0.21 ± 0.01	0.0025 ± 0.0004
	CoA	66.2 ± 1.4	11.11.6	24.7 ± 1.4	0.21 ± 0.01	0.0040 ± 0.0005
	4-PBA	65.9 ± 2.4	11.30.9	22.2 ± 2.3	0.22 ± 0.02	0.0041 ± 0.0008
PKAN[GlyValfs*30]	UT	66.5 ± 1.9	9.00.6	26.0 ± 1.9	0.19 ± 0.01	0.0034 ± 0.0004
	CoA	67.3 ± 1.0	9.30.5	23.8 ± 1	0.20 ± 0.01	0.0066 ± 0.0009
	4-PBA	69.9 ± 1.7	10.60.6	19.7 ± 1.5	0.19 ± 0.01	0.0064 ± 0.001

At least 7,000 motile trajectories analyzed for each condition. *Indicates stop codon.