FIGURE 5.

Schematic illustration of two methods to add platelet derivatives into the scaffolds. (A) 3D printed PLGA frames are immersed in MSC-suspended PRP solution, and then the gelation of PRP is induced by addition of CaCl₂ solution with thrombin to complete the CTE construct. Reproduced with permission from Tang Y. et al. (2021). (B) Biomaterials, MSCs, and PRP are all mixed together before fabrication process to construct the synergistic scaffold. Reproduced with permission from Wu et al. (2020a).