Table 4.
Determinants for TG parameters in linear regression analysis.
| Lag time | ETP | Peak | Time-to-peak | Velocity index | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β-coefficient | β-coefficient | β-coefficient | β-coefficient | β-coefficient | ||||||
| PPP reagent low | UVR | MR | UVR | MR | UVR | MR | UVR | MR | UVR | MR |
| Age, y | 0.003*** | 0.001* | −3.51*** | −4.93*** | −0.005*** | −0.005*** | 0.47*** | 0.24*** | ||
| Sex | 0.17*** | 0.092*** | −69.4*** | −55.5*** | −13.9*** | −15.0*** | 0.168*** | 0.148*** | −5.74*** | −9.88*** |
| BMI, kg/m2 | 0.025*** | 0.008*** | 14.0*** | 12.4*** | 2.55*** | 1.46*** | 0.017*** | 0.013*** | 2.55*** | 0.47*** |
| Smoking | 0.038*** | −14.6*** | −3.19*** | 0.026* | ||||||
| Waist:hip ratio | 1.191*** | 111** | 68.7*** | 21.3* | 0.334* | −0.645*** | 65.7*** | 29.9*** | ||
| Total cholesterol, mg/dL | 0.003*** | −0.006*** | 2.02*** | COL | 0.34*** | COL | 0.003*** | COL | 0.10*** | COL |
| LDL-C, mg/dL | 0.004*** | 0.009*** | 2.24*** | 1.87*** | 0.33*** | COL | 0.005*** | 0.005*** | 0.07*** | COL |
| HDL-C, mg/dL | −0.009*** | COL | 0.45* | 1.79*** | −0.009*** | −0.007*** | −0.09** | −0.49*** | ||
| TGL, mg/dL | 0.002*** | 0.002*** | 0.49*** | 0.63*** | 0.14*** | 0.08*** | 0.001*** | 0.001** | 0.08*** | |
| Blood glucose, mg/dL | 0.001*** | −0.001*** | −0.32** | −0.93*** | 0.16*** | −0.001** | −0.003*** | 0.18*** | 0.04* | |
| CRP, mg/L | 0.042*** | 0.033*** | 20.0*** | 17.0*** | 4.17*** | 3.33*** | 0.022*** | 0.018*** | 2.90*** | 2.28*** |
| PPP reagent | UVR | MR | UVR | MR | UVR | MR | UVR | MR | UVR | MR |
| Age, y | 0.003*** | 0.001** | −3.41*** | −4.77*** | −0.19*** | −0.47*** | −0.003*** | −0.003*** | 0.27*** | 0.11** |
| Sex | 0.096*** | 0.047*** | −68.5*** | −52.8*** | 19.06*** | −19.6*** | 0.152*** | 0.129*** | −10.9*** | −12.8*** |
| BMI, kg/m2 | 0.017*** | 0.005*** | 14.0*** | 12.4*** | 2.05*** | 1.24*** | 0.016*** | 0.01*** | 1.04*** | 0.34*** |
| Smoking | 0.023*** | −0.021* | −16.5*** | −4.53*** | 0.026** | −2.14*** | ||||
| Waist:hip ratio | 0.894*** | 0.132* | 93.4** | 28.86*** | 20.2* | 0.583*** | −0.29** | 28.4*** | 22.6*** | |
| Total cholesterol, mg/dL | 0.002*** | 0.003*** | 1.97*** | 1.67*** | 0.29*** | COL | 0.003*** | 0.004*** | 0.05*** | −0.02* |
| LDL-C, mg/dL | 0.003*** | 2.17*** | COL | 0.27*** | COL | 0.004*** | ||||
| HDL-C, mg/dL | −0.005*** | −0.006*** | 0.15*** | −0.53*** | −0.006*** | −0.008*** | 0.06* | 0.16*** | ||
| TGL, mg/dL | 0.001*** | 0.50*** | 0.30*** | 0.10*** | 0.001*** | 0.04*** | 0.05*** | |||
| Blood glucose, mg/dL | 0.001*** | −0.001*** | −0.34** | −0.96*** | 0.06** | −0.05* | −0.002*** | 0.10*** | 0.04* | |
| CRP, mg/L | 0.031*** | 0.025*** | 20.2*** | 17.1*** | 3.75*** | 3.24*** | 0.019*** | 0.015*** | 2.49*** | 2.13*** |
Linear regression results are presented as β-coefficients and their associated p-values. P-values were indicated as *p < 0.05, **p < 0.01, ***p < 0.001. Sex was coded as ‘'0” for men and ‘'1” for women, hence a negative β-coefficient indicates a decrease in outcome (TG) variable in women compared to men. Smoking was coded as ‘'0” for non-smokers and ‘'1” for current smokers, hence a negative β-coefficient indicates a decrease in outcome (TG) variable in smokers compared to non-smokers. Abbreviations: β-coef., β-coefficient; ETP, Endogenous thrombin potential; UVR, univariate regression analysis; MR, multiple regression analysis; COL, variable excluded from the model because of collinearity (VIF ≥ 10); BMI, Body Mass Index; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; CRP, C-reactive protein.