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. 2022 Jun 16;13:911322. doi: 10.3389/fmicb.2022.911322

Table 2.

Comparison of amino acid consistency of target proteins between fungal and mammalian.

Target proteins Fungal-unique Mammalian homolog The proportion of amino acid sequence identity
Spt14 No PIG-A 40% (S. cerevisiae)
Gwt1 No PIG-W 30% (S. cerevisiae)
Mcd4 No PIG-N 36% (S. cerevisiae)
Chitin synthases Yes
Sec14 No SEC14-like protein 1 11% (S. cerevisiae)
IPC synthase Yes
Hsp90 No HSP 90-alpha 60% (S. cerevisiae)
HSP 90-beta 61% (S. cerevisiae)
Histone deacetylase 2 Yes
Eno1 No Alpha-enolase 63% (S. cerevisiae)
Dihydrolactate dehydrogenase No Dihydroorotate dehydrogenase 30% (Aspergillus)