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. 2022 Jun 16;10:913824. doi: 10.3389/fcell.2022.913824

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Copyright © 2022 Li, Wang, Chen, Li, Zhou, Wang and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The functional role of circCLASP1 in TNBC. (A B) CircCLASP1 drastically attenuated the proliferation of TNBC cells. (C) CircCLASP1 enhanced the tumor suppression effects of Huaier in TNBC cells. (D) CircCLASP1 elicited ER stress in TNBC cells. (E,F) CircCLASP1 promoted Huaier-induced ER stress. *p < 0.05; **p < 0.01.