Fig. 5.

IFN-α2 concentration of patients with COVID-19 and prevalence of aAbs to IFN-α2 in 3456 individuals in the general population. The IFN-α2 concentration in most of the patients with naAbs to IFN-α2 and/or IFN-ω was below the limit of quantification (< 4 pg/mL). A Patients with naAbs to 100 pg/mL of IFN-α2 and/or IFN-ω (n = 8) and patients without naAbs (n = 261) were compared. B Patients with naAbs to 10 ng/mL of IFN-α2 and/or IFN-ω (n = 5) and patients without naAbs (n = 264) were compared. C aAbs to IFN-α2 in the general population were detected using ELISA. The prevalence of aAbs were calculated according to age and sex